Skin Firming

Repairs, tightens and renews the skin, advanced body firming.

Skin Firming

10 x 2.5ml / 0.08 fl oz

Repairs, tightens and renews the skin, advanced body firming.

Firming body treatment with a powerful tightening effect, repairing the dermal matrix, re-epithelializing and regenerating cells.

It is specifically formulated for being introduced by electroporation with extremely high concentrations of the latest generation active ingredients, enhanced with the most advanced delivery and delivery systems.

  • Unboxing:
  • Skin Firming:

    10 ampoules x 2.5 ml. 

    2 ampoules / session.

  • Dropper / Opener:

    5 units.

  • Prospectus:

    Information and instructions for use.


It facilitates opening of the ampoule and the application of the product.


10 ampoules of 2.5 ml of ultra-concentrated product.

Certified for Electroporation

Designed specifically for introduction by electroporation.

  • Droppers

    It facilitates opening of the ampoule and the application of the product.

  • Ultra-concentrated

    10 ampoules of 2.5 ml of ultra-concentrated product.

  • Certified for Electroporation

    Designed specifically for introduction by electroporation.


1. Cleaning.

Clean the area to be treated using a cleaning product (micellar water, cleansing milk ...) and it later can be supplemented with a tonic.

If micropuncture is applied in any area, it can be disinfected with alcohol or chlorhexidine.


2. SC Preparation.

It´s recommended to reduce the thickness of the CS (stratum corneum) as far as possible to facilitate the introduction of active ingredients by electroporation.

We can do it by applying a mild AHA peel or an enzymatic peel.

In medical centers you can combine it with the application of microneedling at 0.25 in localized areas.

In case its not possible to do this step, product may be introduced but it will require a longer application time to achieve their complete introduction.

3. Mesoactives. Preparation.

3.1. Shake the ampule.

Shake the ampoule until its homogenization is complete. Once it has been homogenized, make sure that no product remains on top of the ampoule. You can remove it with small strokes with your finger on the top.


3.2. Open the ampoule with the dropper.

Place the dropper in the ampoule up to the neck and use it to break the top. It should break with a clean sound. Discard the top of the ampoule.


3.3. Place the dropper in the ampoule.

Push the dropper into the ampoule with force until it is fitted.

3.4.Transfer the product to the dropper.

Turn the ampoule upside down and shake so that the product goes down into the dropper. You can apply a light pressure with your fingers on the dropper to suck up the content of ampoule and facilitate the transfer of the product.


4. Application by electroporation.

4.1. Turn on the electroporation device.

Connect the electroporation device and select the treatment to be performed and setting the time or parameters that you want to use at beginning. In the case of working with Mesolux device, we recommend always using phototherapy in active mode since it acts in synergy, enhancing the result of the treatment.


4.2. Product distribution plan.

We recommend planning the area where we want to introduce the product in order to measure the amount to be introduced in each part proportionally. The result will depend on the amount of product introduced in that area, so try to introduce more product in the areas where you want a better result.


4.3. Product application.

The drop application is advisable for its introduction. In this way, remove the cap and apply 2-3 drops of the product on area to be treated, introduce it immediately with the electroporation device by means of small movements on the area, adding more successively until the desired amount of product is introduced.


4.4. Product application. Targeted areas.

As we have seen previously, we will  introduce the product by electroporation through small movements over the same area until we introduce the desired amount.


4.5. Product application. General area (optional).

After introducing the product in the areas where we want a better result, it may be interesting to keep treating the rest of the area not treated in a general way. For this purpose, you can leave a part of the product (25-50%) and apply it directly or if you find that it is introduced too easily and does not allow you to cover the entire area, you can mix it with Mesogel with PDC (dynamic particle control) to have greater volume and to be able to extend the area and / or treatment time.


5. Session ends.

5.1. Cleaning of the excipient.

If you wish, you can remove the excipient that may remain on the skin. You can apply a tonic.


5.2. Post-treatment.

In this step you can finish the treatment in different ways, with the application of a cream, a mask, a facial veil, etc., to give the skin the final ending. Keep in mind that Mesoactives is an ultra-concentrated product that once introduced will not give any type of surface on the skin, so it is advisable to finish the treatment with a product adapted to the client's needs.

You can complement the treatment with products for home use.


5.3. Post-treatment precautions.

The application of techniques such as radiofrequency or laser for 24 hours from the introduction of Mesoactives is totally discouraged, as it could damage the active ingredients and reduce the results.

6. Results.

6.1. Treatment outcomes.

Depending on the patient, the result will be visible approximately the first session, but the final result can be seen after the course of the sessions.

6.2. Results documentation.

We recommend taking photos to document the treatment progress to compare pre-post session and between sessions.



Skin Firming is formulated with a combination of ultra-concentrated skin tightening and regenerating active ingredients to effectively combat body flaccidity, enhanced with re-epithelializing and antioxidant active ingredients.

This combination achieves dermal tissue repair, increases tension and firmness while redensifying, re-epithelializing and protecting the skin, thus achieving an effective and long-lasting firming treatment.




Introduction by electroporation

The world's first line product specifically formulated for introduction by transdermal electroporation.

The introduction by electroporation achieves that the active ingredients penetrate the entire treated tissue, allowing the safe use of concentrations much higher than those used in topical or injectable products.

The specific formulation of electroporation allows the active ingredients to move freedly, allowing their introduction until reaching the target cells, achieving maximum efficiency in the different treatments.

Main active ingredients

Dimethyl Mea

Dimethylaminoethanol or DMAE is a powerful active with a firming and tightening effect. It produces an increase in the production of acetylcholine in the dermis which implies an increase in the firmness of the skin. Moisturizes the dermis with skin filling action and increases the dermal layer resulting in a more toned skin with an immediate firming effect.

Eryngium Maritimum Callus Culture Filtrate

Biotechnological plant stem cells of marine origin that produce powerful skin regeneration. It has its main action in the dermo-epidermal junction, achieving an increase in the production of elastin, collagen and enhancing epidermal renewal.

Nicotiana Benthamiana Hexapeptide-40

Epidermal growth factor (plant-EGF) capable of activating the ERK and AKT pathways. These routes are involved in protein synthesis and cell regeneration in order to recover the state of the extracellular matrix and its capacity for regeneration lost by age.


Peptide containing 414 amino acids identical to the Transforming Growth Factor Beta-2 (plant-TGFβ2), involved in the protein synthesis in the extracellular matrix and the production of epidermal lipids, improving the integrity of the skin, its protection and minimizing the size of the skin. pores. It has an action similar to retinol and retinoic acid in terms of efficiency in the production of collagen I.

Centella Asiatica Extract

Centella Asiatica is extracted from a plant called Gotu Kola that grows in central Asia. It has healing and repairing properties of the dermal matrix by activating fibroblasts, along with moisturizing, antioxidant and soothing properties and improves blood circulation.

Methylsilanol Mannuronate

Organic silicon is an element that is present in a high proportion in the epidermis, dermis and hair to increase the chemical resistance of keratin. It has an anti-free radical action, restructuring / moisturizing action, cytostimulating action on fibroblasts and keratinocytes, and anti-inflammatory and anti-oedematous action.

Palmitoyl Oligopeptide

Palmitoyl Oligopeptide (Pal-GHK) consists of a peptide linked to palmitic acid. The GHK peptide is used as a biological indicator of dermal matrix degradation, forcing the synthesis of new collagen and other components to restructure the matrix through fibroblast activation.

Sodium Hyaluronate

Hyaluronic acid is a glycosaminoglycan capable of absorbing water up to 10,000 times its volume. It is an essential part of the extracellular matrix, retaining water structurally in the skin.

Triticum Vulgare Germ Extract

The wheat germ extract has an outstanding antioxidant power and a high power of healing and cell regeneration. Improves blood circulation and makes skin look healthier. Its antioxidant properties delay skin aging, prevent wrinkles and provide greater skin firmness.



Aqua (water), Alcohol Denat, Propanediol, Dimethyl Mea, Lactic Acid, Eryngium Maritimum Callus Culture Filtrate, Nicotiana Benthamiana Hexapeptide-40, SH-Polypeptide-76, Centella Asiatica Extract, Sodium Hyaluronate, Sorbic Acid, Triticum Vulgare Germ Extract, Ethylhexylglycerin, Glyceryl Polymethacrylate, Hydrochloric Acid, Methylsilanol Mannuronate, Palmitoyl Oligopeptide, Phenoxyethanol, Potassium Sorbate, Propylene Glycol, Tromethamine, Xanthan Gum.